Long-Term Postnatal Follow-Up in Monochorionic TTTS Twin Pregnancies Treated with Fetoscopic Laser Surgery and Complicated by Right Ventricular Outflow Tract Anomalies

Right ventricular outflow tract anomalies (RVOTAs), such as pulmonary stenosis (PS), atresia (PA), and insufficiency (PI), are typical cardiac in monochorionic twins, they complicated by twin-to-twin transfusion syndrome (TTTS). The aim of this study was to conduct a long-term postnatal cardiological evaluation prenatal RVOTAs diamniotic twin pregnancies TTTS treated with fetoscopic laser surgery (FLS) analyze possible predictors congenital heart disease (CHD). Prenatal were retrospectively retrieved from all cases FLS our unit between 2009 2019. Twenty-eight (16 PI, 10 PS, 2 PA) observed out 335 TTTS. Four did not reach the period. CHD present 17 remaining 24 (70.8%), being severe (58.8%; 10/17); nine PS required balloon valvuloplasty, one case biventricular non-compaction cardiomyopathy. risk major increased evidence decreased gestational age at time normalization blood flow across valve. Despite treatment FLS, majority had follow-up.